Sarah Nelson received a pre-doctoral fellowship from the American Heart Association (16PRE27770056). Her research proposal entitled "Structural effects of arrhythmia mutations on the calmodulin-RyR complex" focuses on the regulation of a 2.3 MDa calcium channel ryanodine receptor by a small water soluble protein calmodulin. The latter harbors several naturally occurring mutations, that affect the interaction between the two proteins, rendering the regulation less efficient and ultimately resulting in pathologies